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Colon cancer data reinforce need to reduce unnecessary antibiotic use

New findings from a study presented at the European Society for Medical Oncology (ESMO) World Congress on Gastrointestinal Cancer 2021 (30 June – 3 July) suggest that excessive antibiotic use may increase the risk of colon cancer, particularly among people below the age of 50[1]. The study draws attention to the estimated 65...


Red meat consumption may promote DNA damage-associated mutations in patients with colorectal cancer

While many different risk factors for colorectal cancer (CRC) have been established, the underlying mechanisms are not well known. A recent study published in Cancer Discovery (journal for American Association for Cancer Research) found that high red meat consumption was linked to higher levels of DNA damage in colon cells, ...


Is it time for universal genetic testing in colorectal cancer?

Findings from a recent study show that multigene panel testing of patients with colorectal cancer (CRC) can detect inherited mutations that would not have been identified with guideline-based genetic testing. The prospective study evaluated universal genetic testing, noting that 1 in 6 patients (16%) with CRC have an inherite...


USPSTF final recommendation on CRC screening: 45 is the new 50

The final recommendation from the United States Preventive Services Task Force (USPSTF) builds on draft guidelines issued in October 2020 which state that screening for colorectal cancer (CRC) should now begin at age 45 and not 50 for average-risk individuals in the United States. The recommendation also mandates insurance c...


Periodontal disease can be a potential risk indicator for colorectal cancer

Periodontal disease (PD) is a set of inflammatory conditions that affect the gums and bone that surround and support the teeth. PD is believed to increase systemic inflammation, trigger immune dysfunction, alter the body’s microbiome, and increase the chances of developing certain cancers, including colorectal cancer (CRC) [1]. ...