A recent study published in Nature by Díaz-Gay et al. has linked early-life exposure to a bacterial toxin called colibactin, produced by certain strains of E. coli, with the rise in early-age onset colorectal cancer (EAOCRC). Researchers found colibactin-related DNA mutations were 3.3 times more common in individuals diagnosed with ...
Colorectal cancer often starts as a small polyp that slowly grows until it becomes cancerous. Research indicates that once a polyp reaches around 20mm in size, it can rapidly progress to cancer. Removing these larger polyps early is essential for preventing cancer and avoiding major treatments like surgery or chemotherapy. ...
Colorectal cancer often begins as a small polyp in the colon that slowly grows until it becomes cancerous. Research shows that once a polyp reaches about 20mm in size, it can quickly progress to cancer. Removing these larger polyps early is key to preventing cancer and avoiding major treatments like ...
March 2025 A phase 3 trial presented at the 2025 Gastrointestinal Cancers Symposium showed that three years of aspirin use significantly reduced the risk of recurrence in colorectal cancer patients with PIK3CA mutations. What is PIK3CA? PIK3CA is a gene that is commonly mutated (changed) in many types of cancer ...
March 2025 A recent study suggests that long-term yogurt intake may have a protective effect against colorectal cancer by promoting beneficial changes to the gut microbiome. Researchers focused on Bifidobacterium, a type of beneficial bacteria commonly found in yogurt, and analyzed data from over 132,000 men and women enrolled in ...
The 2025 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium, held from January 23 to 25 in San Francisco, showcased several significant advancements in colorectal cancer research and treatment. Checkmate-8HW Trial: Nivolumab + Ipilimumab Demonstrates Improved Outcomes Over Standard Therapies For MSI-H/dMMR Metastatic Colorectal Cancer What is CheckMate-8HW? ...
January 2025 A study conducted by Cancer Research UK involving more than 500,000 women over a period of 17 years confirmed that dietary calcium lowers the risk of developing colorectal cancer. The study, led by the University of Oxford, followed the intake of 97 different dietary factors - including alcohol ...
September 2024 Findings from the NO-CUT trial were presented at the European Society for Medical Oncology (ESMO) Congress 2024 this September in Barcelona, Spain. The study explored the efficacy of more aggressive initial treatment known as total neoadjuvant therapy followed by non-operative management in patients with mismatch repair proficient (pMMR) ...
September 2024 Findings from research published in the Journal of the National Comprehensive Cancer Network found that when the 5-fluorouracil (5-FU) bolus from combination chemotherapy treatments such as FOLFOX (Folinic acid, 5-Fluorouracil, Oxaliplatin), FOLFIRI (Folinic acid, 5-Fluorouracil, Irinotecan), or FOLFIRINOX (Folinic acid, 5-Fluorouracil, Irinotecan, Oxaliplatin), was removed, it helped to ...
August 2024 Liquid biopsy testing is an important tool in precision oncology that can be used to diagnose cancer and tailor cancer treatments to a patient’s tumour. William Osler Health System in Brampton, Ontario is now the first Canadian hospital to do in-house liquid biopsy testing for cancer care. Precision ...
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