CAR T-cell therapy has transformed the treatment of some blood cancers, but its use in solid tumours, such as colorectal cancer, has been much more challenging. One of the biggest obstacles is finding targets that are found on cancer cells but not on healthy cells, so the treatment can attack ...
May 2026 Researchers at the University of Geneva have developed a new, non-invasive way to help detect colorectal cancer using a simple stool sample. This approach uses artificial intelligence to analyze gut bacteria in much greater detail than before. Colorectal cancer is one of the leading causes of cancer-related deaths ...
A new clinical trial is studying whether a combination of two immunotherapy drugs -botensilimab and balstilimab- can help people with advanced microsatellite stable (MSS) colorectal cancer live longer and improve their quality of life. This study is for people whose colorectal cancer: Is MSS Cannot be removed by surgery Has progressed after all currently ...
January 2026 Some individuals with metastatic colorectal cancer have a specific genetic change called BRAF V600E. This mutation is linked to faster-growing cancer and has traditionally been harder to treat. Researchers are working to find better first-line (initial) treatment options for this group of patients. The study New findings from the BREAKWATER ...
January 2026 Results from the International ColoCare Study were presented at this year's ASCO GI Symposium and found that greater levels of physical activity in the first 2 years after a colorectal cancer (CRC) diagnosis were linked to reduced cancer-related fatigue and improved quality of life in patients with non-metastatic CRC. ...
January 2026 A French study published in The BMJ found that higher intake of food preservatives, additives that are used in industrially processed foods and drinks to extend their shelf life, is linked to a modest increase in the risk of developing cancer. The study While some experimental studies have shown that some preservatives can have a ...
A new study published in the Journal of the American Medical Association looked at cancer deaths in people younger than 50 in the U.S. from 1990 to 2023 to see whether outcomes are improving. Overall, cancer death rates in this age group have dropped by 44% over the past 30 years. Deaths from many major ...
My name is Yvonne McIsaac. I am a 66-year-old retired wife and mother of two amazing sons. Our eldest was taken from us at the age of 38, by the monster I refer to as colorectal cancer. It does not deserve to be capitalized due to the horrific pain it ...
A recent Italian phase II clinical trial (NO-CUT), published in The Lancet Oncology, evaluated whether some patients with stage II–III rectal cancer can safely avoid surgery after responding completely to upfront treatment. The study focused on patients with a common tumor subtype known as pMMR/MSS. pMMR/MSS: proficient mismatch repair / microsatellite stable, describes a "normal" state in cancer cells, especially colorectal ...
A new study - the ATOMIC trial - has found that adding the immunotherapy atezolizumab to standard chemotherapy (FOLFOX) significantly improves outcomes for people with stage III deficient DNA mismatch repair (dMMR) colon tumours - a type of cancer that makes up about 10–15% of non-metastatic colorectal cancers. Key Findings 50% lower risk of cancer recurrence or ...
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