About Iris Karry

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So far Iris Karry has created 86 blog entries.

New First-Line Treatment Option for BRAF V600E–Mutant Metastatic Colorectal Cancer

January 2026  Some individuals with metastatic colorectal cancer have a specific genetic change called BRAF V600E. This mutation is linked to faster-growing cancer and has traditionally been harder to treat. Researchers are working to find better first-line (initial) treatment options for this group of patients.  The study  New findings from the BREAKWATER ...

By |January 27, 2026|Clinical Trials, Research updates|Comments Off on New First-Line Treatment Option for BRAF V600E–Mutant Metastatic Colorectal Cancer

Impact of physical activity on fatigue and quality of life in non-metastatic colorectal cancer

January 2026  Results from the International ColoCare Study were presented at this year's ASCO GI Symposium and found that greater levels of physical activity in the first 2 years after a colorectal cancer (CRC) diagnosis were linked to reduced cancer-related fatigue and improved quality of life in patients with non-metastatic CRC.   ...

By |January 27, 2026|Clinical Trials, Research updates|Comments Off on Impact of physical activity on fatigue and quality of life in non-metastatic colorectal cancer

A Mother’s Perpective

It's Sunday morning, January 11th, 2026 and where do I start?  I'm sitting here reflecting on the loss of my darling son Russell. He was taken from us two and a half years ago at the age of 38. As parents, there's an emptiness in our hearts that can never ...

By |January 26, 2026|Story|Comments Off on A Mother’s Perpective

Nonoperative Management After Total Neoadjuvant Therapy in Rectal Cancer

A recent Italian phase II clinical trial (NO-CUT), published in The Lancet Oncology, evaluated whether some patients with stage II–III rectal cancer can safely avoid surgery after responding completely to upfront treatment. The study focused on patients with a common tumor subtype known as pMMR/MSS.  pMMR/MSS: proficient mismatch repair / microsatellite stable, describes a "normal" state in cancer cells, especially colorectal ...

By |December 19, 2025|Clinical Trials, Research updates|Comments Off on Nonoperative Management After Total Neoadjuvant Therapy in Rectal Cancer

The ATOMIC study: atezolizumab plus FOLFOX chemotherapy significantly improves disease-free survival and reduces the risk of recurrence in stage III colon cancer

A new study - the ATOMIC trial - has found that adding the immunotherapy atezolizumab to standard chemotherapy (FOLFOX) significantly improves outcomes for people with stage III deficient DNA mismatch repair (dMMR) colon tumours - a type of cancer that makes up about 10–15% of non-metastatic colorectal cancers.  Key Findings  50% lower risk of cancer recurrence or ...

By |November 19, 2025|Clinical Trials, Research updates|Comments Off on The ATOMIC study: atezolizumab plus FOLFOX chemotherapy significantly improves disease-free survival and reduces the risk of recurrence in stage III colon cancer

Ultraprocessed Food Consumption and Risk of Early-Onset Colorectal Cancer Precursors Among Women

November 2025  A new study published in JAMA Oncology found that women who eat more ultraprocessed foods (UPFs) such as packaged snacks, sugary drinks, and processed meats may have a higher risk of developing early precancerous growths in the colon.  The study followed over 29,000 female nurses under age 50 for more than two decades. Researchers ...

By |November 19, 2025|Blog, Research updates|Comments Off on Ultraprocessed Food Consumption and Risk of Early-Onset Colorectal Cancer Precursors Among Women

Microplastics in the Gut Linked to Colorectal Cancer-Like Patterns

November 2025 New research from the microONE project (CBmed GmbH, Austria) suggests that microplastics may impact gut health by altering the microbiome. Using human stool samples to create controlled gut cultures, researchers exposed the samples to five common microplastics - polystyrene, polypropylene, low-density polyethylene, poly(methyl methacrylate), and polyethylene terephthalate - ...

By |November 3, 2025|Clinical Trials, Research updates|Comments Off on Microplastics in the Gut Linked to Colorectal Cancer-Like Patterns

Rectal Bleeding Identified as Key Predictor of Early-Onset Colorectal Cancer

November 2025 A recent study presented at the American College of Surgeons Clinical Congress 2025 highlights rectal bleeding as a strong predictor of early-onset colorectal cancer (EOCRC) in individuals under 50. Conducted by Jin et al., the retrospective cohort analysis included 443 patients undergoing colonoscopy between 2021 and 2023, of ...

By |November 3, 2025|Clinical Trials, Research updates|Comments Off on Rectal Bleeding Identified as Key Predictor of Early-Onset Colorectal Cancer

Do GLP-1 Medications Affect Cancer Risk?

The use of glucagon-like peptide 1 receptor agonist (GLP-1 RA) medications, originally developed for the management of type 2 diabetes, has surged in recent years due to the approval for expanded use for chronic weight management1. A new study looked at whether people who take GLP-1 RA-medications like semaglutide (Ozempic®, ...

By |September 22, 2025|Clinical Trials, Research updates|Comments Off on Do GLP-1 Medications Affect Cancer Risk?

New study shows how the microbiome can impact the effectiveness of immunotherapy treatment

Researchers have discovered a new type of gut bacteria, called YB328, that may help cancer treatments work better. This bacterium was found in patients with lung and stomach cancers who responded well to a type of immunotherapy called PD-1 blockade, a treatment that helps the immune system attack cancer. Currently, ...

By |August 27, 2025|Clinical Trials, Research updates|Comments Off on New study shows how the microbiome can impact the effectiveness of immunotherapy treatment
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