{"id":13861,"date":"2024-05-28T14:00:06","date_gmt":"2024-05-28T14:00:06","guid":{"rendered":"https:\/\/www.colorectalcancercanada.com\/?p=13861"},"modified":"2024-06-04T12:11:14","modified_gmt":"2024-06-04T12:11:14","slug":"etude-de-phase-ii-visant-a-evaluer-lefficacite-du-qbeco-ssi-dans-le-traitement-du-cancer-colorectal-qui-sest-propage-au-foie-periop-06","status":"publish","type":"post","link":"https:\/\/www.colorectalcancercanada.com\/fr\/blogue\/etude-de-phase-ii-visant-a-evaluer-lefficacite-du-qbeco-ssi-dans-le-traitement-du-cancer-colorectal-qui-sest-propage-au-foie-periop-06\/","title":{"rendered":"\u00c9tude de phase II visant \u00e0 \u00e9valuer l&rsquo;efficacit\u00e9 du QBECO SSI dans le traitement du cancer colorectal qui s&rsquo;est propag\u00e9 au foie (PERIOP-06)"},"content":{"rendered":"<p><span data-contrast=\"none\">\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">PERIOP-06 est un essai clinique de phase II qui \u00e9valuera l&rsquo;efficacit\u00e9 d&rsquo;un m\u00e9dicament connu sous le nom d&rsquo;immunomodulateur sp\u00e9cifique de site (SSI) chez des patients qui ont pr\u00e9vu de subir une intervention chirurgicale pour retirer un cancer colorectal qui s&rsquo;est propag\u00e9 au foie (m\u00e9tastases). Le SSI \u00e0 l&rsquo;\u00e9tude, appel\u00e9 QBECO, est con\u00e7u pour r\u00e9tablir une fonction immunitaire normale dans le tractus gastro-intestinal et les organes connexes, y compris le foie, afin d&rsquo;\u00e9liminer et de pr\u00e9venir le cancer.\u00a0 <\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">L&rsquo;objectif principal de de l&rsquo;\u00e9tude PERIOP-06 est d&rsquo;\u00e9valuer si l&rsquo;administration de la SSI QBECO aux patients atteints de cancer colorectal m\u00e9tastatique avant et apr\u00e8s leur chirurgie colorectale peut r\u00e9duire les risques de progression du cancer.\u00a0\u00a0 L&rsquo;objectif de cette \u00e9tude est de d\u00e9terminer si cette approche est meilleure ou non que la norme de soins. La norme de soins est d\u00e9finie comme les soins que la plupart des gens re\u00e7oivent pour le cancer colorectal m\u00e9tastatique. Il n&rsquo;existe actuellement aucun m\u00e9dicament de r\u00e9f\u00e9rence administr\u00e9 avant ou apr\u00e8s une intervention chirurgicale pour emp\u00eacher la propagation de votre cancer. Pour en savoir plus sur cette \u00e9tude, consultez la vid\u00e9o ci-dessous (en anglais).\u00a0 <\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Au Canada, cette \u00e9tude se d\u00e9roulera dans deux h\u00f4pitaux participants en Ontario : <\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Toronto, Ontario <\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Centre des sciences de la sant\u00e9 Sunnybrook\u00a0 <\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Chercheur principal : Dr. Paul Karanicolas <\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Recrutement actif <\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Contact : Grace Xu, <a href=\"mailto:grace.xu@sri.utoronto.ca\" data-linkindex=\"0\">grace.xu@sri.utoronto.ca<\/a><\/span><\/p>\n<p><span data-contrast=\"none\">\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Ottawa, Ontario <\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Institut de recherche de l&rsquo;h\u00f4pital d&rsquo;Ottawa <\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Chercheur principal : Dr. Rebecca Auer <\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Recrutement actif <\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Contact : Rose LeClerc, <a href=\"mailto:roleclerc@ohri.ca\">roleclerc@ohri.ca <\/a><\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Pour plus d&rsquo;informations sur cet essai : <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT05677113?intr=qbeco%20ssi&amp;rank=3\" target=\"_blank\" rel=\"noopener\">https:\/\/clinicaltrials.gov\/study\/NCT05677113?intr=qbeco%20ssi&amp;rank=3 <\/a><\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Vid\u00e9o int\u00e9gr\u00e9e : <a href=\"https:\/\/youtu.be\/nQ36DDs8IRg\" target=\"_blank\" rel=\"noopener\">https:\/\/youtu.be\/nQ36DDs8IRg<\/a><\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335557856&quot;:16777215,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<p><iframe title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/nQ36DDs8IRg?si=ibtpbV3ged0EEL81\" width=\"560\" height=\"315\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0\u00a0 PERIOP-06 est un essai clinique de phase II qui \u00e9valuera l&rsquo;efficacit\u00e9 d&rsquo;un m\u00e9dicament connu sous le nom d&rsquo;immunomodulateur sp\u00e9cifique de site (SSI) chez des patients qui ont pr\u00e9vu de subir une intervention chirurgicale pour retirer un cancer colorectal qui s&rsquo;est propag\u00e9 au foie (m\u00e9tastases). Le SSI \u00e0 l&rsquo;\u00e9tude, appel\u00e9 <a href=\"https:\/\/www.colorectalcancercanada.com\/fr\/blogue\/etude-de-phase-ii-visant-a-evaluer-lefficacite-du-qbeco-ssi-dans-le-traitement-du-cancer-colorectal-qui-sest-propage-au-foie-periop-06\/\">&#8230;<\/a><\/p>\n","protected":false},"author":5,"featured_media":11982,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false,"footnotes":""},"categories":[42,57,98],"tags":[],"class_list":["post-13861","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blogue","category-essais-cliniques","category-research-updates-fr"],"_links":{"self":[{"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/posts\/13861","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/comments?post=13861"}],"version-history":[{"count":0,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/posts\/13861\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/media\/11982"}],"wp:attachment":[{"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/media?parent=13861"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/categories?post=13861"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/tags?post=13861"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}