{"id":18228,"date":"2026-04-01T13:40:58","date_gmt":"2026-04-01T13:40:58","guid":{"rendered":"https:\/\/www.colorectalcancercanada.com\/?post_type=drug&#038;p=18228"},"modified":"2026-04-08T16:06:05","modified_gmt":"2026-04-08T16:06:05","slug":"irinotecan","status":"publish","type":"drug","link":"https:\/\/www.colorectalcancercanada.com\/fr\/drug\/irinotecan\/","title":{"rendered":"Irinotecan"},"content":{"rendered":"<p><strong>Indication :<\/strong><\/p>\n<p>Pour le traitement du cancer colorectal m\u00e9tastatique (CCRm) ; il est le plus souvent utilis\u00e9 en association avec le 5-fluorouracile et la leucovorine dans le cadre du protocole FOLFIRI, soit en traitement de premi\u00e8re intention, soit apr\u00e8s un traitement ant\u00e9rieur. Il peut \u00e9galement \u00eatre utilis\u00e9 en monoth\u00e9rapie apr\u00e8s progression sous traitement \u00e0 base de fluoropyrimidine et est inclus dans le protocole FOLFOXIRI pour certains patients en bonne condition physique atteints d&rsquo;une maladie avanc\u00e9e. Son utilisation est principalement limit\u00e9e au cancer colorectal avanc\u00e9 ou m\u00e9tastatique et n&rsquo;est pas syst\u00e9matiquement indiqu\u00e9e en traitement adjuvant pour le cancer du c\u00f4lon \u00e0 un stade pr\u00e9coce.<\/p>\n","protected":false},"template":"","crc_subtype":[401],"drug_stage":[402],"therapy_line":[418],"health_canada_approval":[404],"cda_review":[],"cda_recommendation":[],"inesss_review":[],"inesss_recommendation":[],"pcpa_status":[],"public_reimbursement":[411,410,454,450,451,414,457,453,413,412,452,456,455],"class_list":["post-18228","drug","type-drug","status-publish","hentry","crc_subtype-none-fr","drug_stage-iv-fr","therapy_line-premiere-ligne","health_canada_approval-approved-fr","public_reimbursement-alberta-fr","public_reimbursement-colombie-britannique-fr","public_reimbursement-i-p-e","public_reimbursement-manitoba-fr","public_reimbursement-n-b","public_reimbursement-ns-fr","public_reimbursement-nt","public_reimbursement-on","public_reimbursement-qc-fr","public_reimbursement-sk-fr","public_reimbursement-t-n-l","public_reimbursement-t-n-o","public_reimbursement-yn"],"_links":{"self":[{"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/drug\/18228","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/drug"}],"about":[{"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/types\/drug"}],"wp:attachment":[{"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/media?parent=18228"}],"wp:term":[{"taxonomy":"crc_subtype","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/crc_subtype?post=18228"},{"taxonomy":"drug_stage","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/drug_stage?post=18228"},{"taxonomy":"therapy_line","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/therapy_line?post=18228"},{"taxonomy":"health_canada_approval","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/health_canada_approval?post=18228"},{"taxonomy":"cda_review","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/cda_review?post=18228"},{"taxonomy":"cda_recommendation","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/cda_recommendation?post=18228"},{"taxonomy":"inesss_review","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/inesss_review?post=18228"},{"taxonomy":"inesss_recommendation","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/inesss_recommendation?post=18228"},{"taxonomy":"pcpa_status","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/pcpa_status?post=18228"},{"taxonomy":"public_reimbursement","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/public_reimbursement?post=18228"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}