{"id":17953,"date":"2026-03-09T12:54:11","date_gmt":"2026-03-09T12:54:11","guid":{"rendered":"https:\/\/www.colorectalcancercanada.com\/?post_type=drug&#038;p=17953"},"modified":"2026-03-30T15:43:53","modified_gmt":"2026-03-30T15:43:53","slug":"trifluridine-tipiracil","status":"publish","type":"drug","link":"https:\/\/www.colorectalcancercanada.com\/fr\/drug\/trifluridine-tipiracil\/","title":{"rendered":"Trifluridine\/tipiracil"},"content":{"rendered":"<p><strong>Indication<\/strong><\/p>\n<p>Traitement des patients adultes atteints d&rsquo;un cancer colorecal m\u00e9tastatique ayant d\u00e9j\u00e0 re\u00e7u les traitements disponibles , notamment les chimioth\u00e9rapies \u00e0 base de fluoropyrimidine, d&rsquo;oxaliplatine et d&rsquo;irinot\u00e9can, les agents biologiques anti-VEGF et, s&rsquo;ils sont de type RAS sauvage, les agents anti-EGFR, ou qui ne sont pas candidats \u00e0 ces traitements.<\/p>\n<p>Lonsurf en monoth\u00e9rapie est indiqu\u00e9 dans le traitement des patients adultes atteints d&rsquo;un cancer gastrique m\u00e9tastatique ou d&rsquo;un ad\u00e9nocarcinome de la jonction gastro-\u0153sophagienne, qui ont d\u00e9j\u00e0 \u00e9t\u00e9 trait\u00e9s par au moins deux lignes de chimioth\u00e9rapie, notamment par une fluoropyrimidine, un platine et soit un taxane, soit l&rsquo;irinot\u00e9can, et, le cas \u00e9ch\u00e9ant, par un traitement ciblant HER2\/neu.<\/p>\n","protected":false},"template":"","crc_subtype":[401],"drug_stage":[402],"therapy_line":[],"health_canada_approval":[404],"cda_review":[405],"cda_recommendation":[406],"inesss_review":[407],"inesss_recommendation":[408],"pcpa_status":[409],"public_reimbursement":[411,410,454,451,453,413,412],"class_list":["post-17953","drug","type-drug","status-publish","hentry","crc_subtype-none-fr","drug_stage-iv-fr","health_canada_approval-approved-fr","cda_review-completed-fr","cda_recommendation-positive-fr","inesss_review-termine-fr","inesss_recommendation-positive-fr","pcpa_status-completed-fr","public_reimbursement-alberta-fr","public_reimbursement-colombie-britannique-fr","public_reimbursement-i-p-e","public_reimbursement-n-b","public_reimbursement-on","public_reimbursement-qc-fr","public_reimbursement-sk-fr"],"_links":{"self":[{"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/drug\/17953","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/drug"}],"about":[{"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/types\/drug"}],"wp:attachment":[{"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/media?parent=17953"}],"wp:term":[{"taxonomy":"crc_subtype","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/crc_subtype?post=17953"},{"taxonomy":"drug_stage","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/drug_stage?post=17953"},{"taxonomy":"therapy_line","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/therapy_line?post=17953"},{"taxonomy":"health_canada_approval","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/health_canada_approval?post=17953"},{"taxonomy":"cda_review","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/cda_review?post=17953"},{"taxonomy":"cda_recommendation","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/cda_recommendation?post=17953"},{"taxonomy":"inesss_review","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/inesss_review?post=17953"},{"taxonomy":"inesss_recommendation","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/inesss_recommendation?post=17953"},{"taxonomy":"pcpa_status","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/pcpa_status?post=17953"},{"taxonomy":"public_reimbursement","embeddable":true,"href":"https:\/\/www.colorectalcancercanada.com\/fr\/wp-json\/wp\/v2\/public_reimbursement?post=17953"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}