Publication: Clinically meaningful survival benefit in refractory mCRC

May 3, 2019

Colorectal Cancer Canada (CCC) is proud to announce the publication of the paper entitled “What is clinically meaningful survival benefit in refractory metastatic colorectal cancer?” which was the result of a consensus meeting hosted by CCC. We are very thankful for the time and effort that went into producing the article, and hope that it is helpful in addressing issues of equity and transparency in health technology assessment.

RELATED ARTICLES

Where is your stress coming from?

Author: Carly Fleming, Registered Psychotherapist, Everwell Counsellin [...]

Does colon tumour location play a role in metastasis and survival?

October 2023 Despite being part of the same organ, right- and left-si [...]

Gut Microbiome Variations and Colorectal Cancer Risk

October 2023 Recent findings presented at United European Gastroent [...]

Impact of Cancer on the Family: Coping and Supporting Each Other Through a Colorectal Cancer Diagnosis

A colorectal cancer diagnosis is life-changing and affects not only th [...]

Predicting recurrence in CRC using post-operative circulating tumour DNA

September 2023 Circulating tumour DNA (ctDNA) refers to the fragmen [...]

Exercise linked to lower mortality risk across different cancer types

September 2023 After a cancer diagnosis, the impact of exercise on [...]

Coping with Metastatic Cancer

Learning that you have metastatic cancer can be a physically and emoti [...]

The FDA approves Lonsurf plus bevacizumab for metastatic colorectal cancer

August 2023 The US Food and Drug Administration (FDA) has approved [...]

Liver transplant improves survival for certain patients with colorectal cancer liver metastases

August 2023 A recent study demonstrated that a liver transplant pro [...]

What does Research Say? The Impact of Meditation on Cancer-Treatment Side Effects.

If you or a loved one has been diagnosed with cancer, you know that it [...]

Fruquintinib significantly extends survival in refractory metastatic colorectal cancer

July 2023 Fruquintinib is a small molecule inhibitor of the vascula [...]

Chemotherapy sequence in advanced colorectal cancer

July 2023 Phase III studies have shown the advantage of combining c [...]

Patient-reported outcomes from the PROSPECT trial: treatment for locally advanced rectal cancer

A recent analysis from the PROSPECT trial examined trends in patient-r [...]

Trastuzumab deruxtecan shows activity in HER2+ metastatic colorectal cancer

The DESTINY-CRC01 trial was one of the first studies to show that the [...]

Stress Management: What stress does to your body and how to reduce it.

Some forms of stress are not harmful to our body such as the stress we [...]

Combination of patient, provider outreach boosts CRC screening in high-risk individuals

May 2023 Recent data presented at Digestive Disease Week in Chicago [...]

A dedicated patient navigator improved FIT return rates by nearly 38%

May 2023 A patient navigator helps patients through the healthcare [...]

Preparing for an upcoming appointment

Attending a medical appointment can be daunting for some people. It is [...]

Greater levels of inflammation after surgery and prior to chemotherapy associated to poorer survival in stage III colon cancer

April 2023 A recent study published in JAMA Oncology found that amo [...]

Financial toxicity of cancer may impact partner’s quality of life

April 2023 A recent study published in JAMA Network Open showed tha [...]

Novel immunotherapy combination showed high efficacy among patients with microsatellite stable metastatic colorectal cancer

March 2023 - Results from a phase I study presented at the American So [...]

The psychological impact of surviving colorectal cancer

March 2023 -A German study published in BMC Cancer explored the emotio [...]

Levels of cell-free DNA do not impact ctDNA detection in patients with CRC

January 2023 There is increasing evidence to support the use of cir [...]

Trifluridine plus tipiracil and bevacizumab is a new standard of care for refractory metastatic colorectal cancer

January 2023 Findings from the phase III SUNLIGHT trial were presente [...]

The CheckMate 8HW study: A study of nivolumab, nivolumab plus ipilimumab, or investigator’s choice chemotherapy for the treatment of participants with deficient mismatch repair (dMMR) / microsatellite instability high (MSI-H) metastatic colorectal cancer (mCRC)

Locations: BC, AB, ON, QC Status: currently recruiting Trial descr [...]

Exercise during chemo may help beat the treatment’s debilitating effects

November 2022 A new study involving patients with different cancer [...]

Differences in the gut microbiome by physical activity and BMI among colorectal cancer patients

November 2022 To better understand the role of the gut microbiome i [...]

Diverticular disease associated with increased risk of multiple cancers

October 2022 A recent study published in the Journal of the Nationa [...]

Recent study provokes controversy about the effectiveness of colonoscopy as a screening test

Earlier this month, controversial news headlines emerged: “Colonoscopi [...]

EXCEL: Technology and Exercise Adherence

Location: Canada-wide Status: Currently recruiting Trial Descrip [...]

The FRESCO-2 trial: exploring treatment options for patients with metastatic colorectal cancer

Findings from the global FRESCO-2 trial showed that a drug called fruq [...]

Effect of physical activity on disease-free survival in patients receiving adjuvant therapy

Findings from a study published in the Journal of Clinical Oncology de [...]

Understanding ulcerative colitis: a risk factor for colorectal cancer

Ulcerative colitis is a chronic inflammatory bowel disease that affect [...]

Understanding Crohn’s disease: a risk factor for colorectal cancer

Crohn’s disease is a chronic (long-term) inflammatory disease that can [...]

Q&A with Dr. Brandon Sheffield, Pathologist

In this Q&A, Dr. Brandon Sheffield, Pathologist with the William O [...]

Q&A with Suzanne Zwicker, clinical pharmacist

In this Q&A, Suzanne Zwicker, Clinical Pharmacist on the National [...]

ESMO World Congress on Gastrointestinal Cancer 2022

July 2022 The annual ESMO World Congress on Gastrointestinal (GI) C [...]

Regional Therapy for Colorectal Cancer Liver Metastases

July 2022 Patients who have colorectal cancer that has spread to th [...]

Minimal Residual Disease (MRD) and CRC

June 2022 Minimal residual disease (MRD) is a term that refers to cance [...]

ASCO 2022

June 2022. Key Updates from ASCO 2022 1. Immunotherapy treatment res [...]

HER2 Therapies for Patients with mCRC

May 2022. Image source: https://www.whathealth.com/breastcancer/her2rec [...]

Overall survival associated with Pembrolizumab (Keytruda) vs. Chemotherapy in MSI-H/dMMR mCRC

May 2022 The KEYNOTE-177 trial is a landmark study in colorectal ca [...]

Alcohol intake and risk of alcohol-related cancer

April 2022. A new study from Australia found that heavy drinking in [...]

Associations between unprocessed red meat and processed meat with risk of recurrence and mortality in patients with stage III colon cancer

April 2022. A study published in JAMA Network Open investigated whe [...]

Can weight loss in adulthood reduce the risk of developing colorectal adenomas?

March 2022. While obesity is a known risk factor for colorectal can [...]

The emotional impact of a colorectal cancer diagnosis

https://youtu.be/-Oi2jBJDUNc February 2022. Join Patient Support Spe [...]

ASCO GI 2022: Trial evaluating immunotherapy in neoadjuvant setting for the treatment of locally advanced rectal cancer

January 2022 Total neoadjuvant therapy (TNT) is a standard approach [...]

ASCO GI 2022: Key considerations about oxaliplatin for the treatment of mCRC

January 2022 Oxaliplatin is an important intravenous chemotherapy d [...]

Webinar: Supporting individuals awaiting an ostomy and those living with one

January 2022. Laura Ferguson, a current ileostomy patient, and Karen Br [...]

Webinar: Intimacy and Cancer

Join Chana, our Patient Support Specialist, as she sits down to a cand [...]

Left Vs. Right Sided Colorectal Tumors: A Clinical Presentation by Dr. Scott Berry

Join Dr. Scott Berry, Professor & Department Head, Department of O [...]

Ask a Doctor : Q&A on Radiotherapy

Left: Laura A. Dawson, MD, FRCPC, Princess Margaret Cancer Centre/Univ [...]

FDA clears new drug application for CAR-T cell therapy for the treatment of solid tumours

This month, the Food and Drug Administration (FDA) cleared an investig [...]

Update on the role of low-dose aspirin in colorectal cancer prevention

In 2016, the United States Preventive Services Task Force (U [...]

Interview: Jason Abramovitch

In 2020, Jason was diagnosed with stage 3b colorectal cancer at age 36. In [...]

Living with LARS: Naturopathy

Dr. Megan Bernard, naturopathic doctor, discusses a variety of tips and su [...]

Living with LARS: Nutrition

Nutritionist Jill Haverstock discusses a variety of tips and suggestions t [...]

Cancer Screening in Canada: Interview with Dr. Mel Borins

Dr. Mel Borins is a family practitioner based in Toronto, Ontario. He crea [...]

Interview: Jason from Man Up to Cancer

Jason Abramovitch is an early age onset stage 3b colon cancer survivor who [...]

Acupressure and Auricular Therapy for Symptom Management

On December 3rd 2021, Physiotherapist Thi Tran gave a compelling session o [...]

Underrepresentation in cancer clinical trials

November 2021 Findings from a recent study published in JAMA Networ [...]

First-line nivolumab plus low-dose ipilimumab for MSI-high/MMR-deficient mCRC

November 2021 Findings from phase II of the CheckMate-142 trial sho [...]

Highlights from the phase III EPOCH trial

The EPOCH trial is the first phase III international study evaluating the [...]

Impact of tumour vaccine on increasing anti-cancer response

Immunotherapy has revolutionized the way cancer is treated by boosting [...]

ESMO 2021 Congress: CRC highlights

Colorectal (CRC) cancer screening and diagnosis during the COVID-19 pa [...]

Antibiotic use and colon cancer: more evidence of link

A Swedish population study published this month in the Journal of the [...]

Clinical implications of the ongoing GALAXY trial

Adjuvant (post-surgical) chemotherapy is useful in reducing the risk o [...]

Developing a better fecal immunochemical test (FIT) for colon cancer screening

The fecal immunochemical test (FIT) is a widely used colorectal cancer [...]

Colon cancer data reinforce need to reduce unnecessary antibiotic use

New findings from a study presented at the European Society for Medica [...]

Red meat consumption may promote DNA damage-associated mutations in patients with colorectal cancer

While many different risk factors for colorectal cancer (CRC) have bee [...]

Is it time for universal genetic testing in colorectal cancer?

Findings from a recent study show that multigene panel testing of patients [...]

USPSTF final recommendation on CRC screening: 45 is the new 50

The final recommendation from the United States Preventive Services Ta [...]

Periodontal disease can be a potential risk indicator for colorectal cancer

Periodontal disease (PD) is a set of inflammatory conditions that affect t [...]

FDA Oks marketing of first AI device used to detect lesions during colonoscopy

The US Food and Drug Administration (FDA) recently approved the market [...]

Foods that Fight Cancer: Recipe Videos

We've posted some new recipe videos on our sister site, Foods that Fight C [...]

OICR Translational Research Conference

The Ontario Cancer Research Institute (OICR) held a conference on Tran [...]

Addressing cancer disparities in Canada

April is Diversity Month dedicated to celebrating and honouring all in [...]

The role of maintenance strategies in metastatic colorectal cancer

Results from a systematic review published in JAMA Oncology found that [...]

Liquid biopsy for colorectal cancer could guide therapy for tumours

A study published in the Journal of Clinical Oncology Precision Oncology s [...]

ASCO names molecular profiling of gastrointestinal cancer “Advance of the Year”

Molecular profiling in gastrointestinal (GI) cancer has been named by [...]

The Importance of Self-care for Caregivers

Your physical, emotional and mental well-being are vital to your ability t [...]

Rates of eligible people missing timely cancer screenings: A Canadian analysis

New findings from the University of Alberta published in the Journal of th [...]

Postsurgical disease recurrence in stage I to III colorectal cancer may be predicted by ctDNA

Findings from a recent study presented at the 2021 Gastrointestinal Ca [...]

Survey Results: Never Too Young

Colorectal cancer is the second most diagnosed cancer in Canada. Twent [...]

Statins reduced risk of colorectal cancer in meta-analysis

10 December 2020Findings from a recent study showed that people who regula [...]

Hepatic Artery Infusion pumps in patients with colorectal cancer with liver metastases

22 December 2020 Hepatic Artery Infusion (HAI) chemotherapy is sometime [...]

“Test all patients with cancer”: 1 in 8 have inherited mutations

November 2020 Findings from a recent study conducted by the Mayo Clinic [...]

Rectal cancer management: do all patients need to undergo surgery?

The non-surgical management or “watch-and-wait” approach for rectal c [...]

Palliative care for young adults is a growing reality in CRC

The incidence of colorectal cancer (CRC) is rising among young adults, who [...]

OPTIMISTICC Research Program sheds light on importance of gut microbiome in colorectal cancer development and treatment

Opportunity to Investigate the Microbiome’s Impact on Science and Treatmen [...]

Cancer Survivors Urgently Need Better Nutritional Support

New findings from a study conducted at the University of Sheffield in [...]

Intimacy and Colorectal Cancer

Sexuality and relationships during and after cancer is extremely impor [...]

Understanding early-onset colorectal cancer: why are cases on the rise?

Chadwick Boseman’s death from colorectal cancer (CRC) at age 43 was a shoc [...]

World Metastatic Colorectal Cancer Day

Today, Wednesday September 30th, is World Metastatic Colorectal Cancer Day [...]

Optimal sequencing strategies in metastatic colorectal cancer

Dr. Heinz-Josef Lenz, MD, discusses optimal sequencing strategies for [...]

ESMO Virtual Congress 2020: Colorectal cancer highlights

The European Society for Medical Oncology ESMO Virtual Congress 2020 t [...]

Welcoming Our Newest CCC Ambassador, Jesse Fishman!

Jesse Fishman is a 17-year-old hockey player, currently playing for the Ki [...]

Do young diabetes patients need early CRC screening?

12 August 2020 Recent findings from a Swedish cohort study found that p [...]

Cancer Recurrence amid COVID-19: Robin’s Story

It was the day of the lockdown. My family doctor called. “The colorectal c [...]

Never Too Young Survey Launch

Fill out the survey! The world was shocked late last week as we learned a [...]

Gut bacteria found to modulate response to cancer immunotherapy

Previous data have shown that certain species of intestinal bacteria not o [...]

Your Seasonal Guide to Cancer-Fighting Foods

As we transition into autumn, take a moment to appreciate the seasonal pro [...]

Psychosocial support for patients with cancer during COVID-19

The COVID-19 pandemic has presented countless new challenges in cancer car [...]

COVID-19 NEWSLETTER

The COVID-19 pandemic situation is constantly evolving. Canada is slowly r [...]

CRC with peritoneal metastases: CRS-HIPEC refinements

Results of several new studies provide important perspectives on the use o [...]

Four actionable targets for metastatic colorectal cancer

In the past two years, findings from important clinical trials are shaping [...]

Patient Group Pathway Model to Accessing Cancer Clinical Trials and RWE Conference

Hold the Date! On behalf of Colorectal Cancer Canada (CCC), you are cordi [...]

Lynch Syndrome, Explained

What is Lynch Syndrome? Lynch syndrome is a genetically inherited conditi [...]

COVID-19 PATIENT SURVEY REPORT

Coronavirus has taken the world by storm since the beginning of 2020, and [...]

PUSH FOR YOUR TUSH VIRTUAL EVENT 2020

To ensure the health and safety of our participants, volunteers, staff and [...]

Gastrointestinal Highlights from last month’s ASCO 2020 Meeting

The American Society of Clinical Oncology (ASCO) held its annual meeting a [...]

How is colorectal cancer care changing in the era of COVID-19?

In just a few months, coronavirus (COVID-19) has transformed our lives. De [...]

Meatless for CRC prevention

It has been known for millennia that what we eat can be powerful medicine [...]

Immunotherapy treatment proves to be superior to chemotherapy for a specific subset of patients with mCRC

The last few decades have seen important advances in colorectal cancer tre [...]

Push For Your Tush volunteers spread the word

Co-leads of Push For Your Tush Ottawa share their connection to the cause [...]

2,700 VISITORS PASS THROUGH GIANT COLON TOUR AT THE SHERBROOKE HALF MARATHON

The Centre de recherche of the Centre hospitalier universitaire de Sherbro [...]

Colorectal cancer screening in Ontario is changing to the FIT

On June 24, 2019, colorectal cancer screening in Ontario is changing to th [...]

Remembering the “Father of Heredity Cancer” Dr. Henry Lynch

Today we remember Dr. Henry Lynch, esteemed researcher and father of hered [...]

Kicking cancer’s ass on the golf course

On Tuesday, July 16, Colorectal Cancer Canada (CCC) held our third annual [...]

Increasing rates of colon & rectal cancers in young people

Researchers with the World Health Organization confirm increased rates of [...]

CCC attends Early Age Onset Colorectal Cancer Summit in New York City

Last Thursday and Friday, Morgan Kennedy, CCC’s Never Too Young Program Ma [...]

Giant Colon visits University of Montreal Hospital Centre

Today, the Giant Colon Tour stopped at the University of Montreal Hospital [...]

CCC’s PUSH FOR YOUR TUSH SPARKS PARTNERSHIP WITH THE TORONTO PROFESSIONAL FIRE FIGHTERS ASSOCIATION

Most people do not know that cancer is the number one cause of death among [...]

March is Colorectal Cancer Awareness Month

March is Colorectal Cancer Awareness Month! Colorectal cancer may touch yo [...]

Sponsors